Investigating the function of paternally-inherited histones during early embryogenesis.
I am studying factors that may be regulating selective oncogenic Notch1 signaling in T-cell Acute Lymphoblastic Leukemia, using biochemical and in vivo studies.
Investigating the role of ASXL3 in Polycomb repression and characterizing the transcriptional plasticity required for neural differentiation
Alyssa is broadly interested in the cellular mechanisms governing mammalian tissue development, disease, and repair.
Elucidating the downstream mechanisms by which FMOs, flavin-containing monooxygenases, extend lifespan in C. elegans and mice.